List of Biotech Companies in the USA

Last updated 21 October 2026

There are 4,528 biotech companies in the USA, one in every 14,106 US companies. Most of them are small: three in four have one to four people, and only 212 firms employ 50 people or more. One in fifteen biotech firms is based in New York, San Diego, Cambridge, Phoenix and Denver. Below you find the largest biotech firms in the USA, the cities where they cluster, how many started this year and which are the oldest. The full list with addresses, phone numbers and email is in our US company database or through the Company Data API.

4,528 companies indexed · Data counted on 21 October 2026

Companies4,5281 in14,106 US companiesCities1,762Largest cityNew York 78Sole traders2%Employees1-4 (77%)Revenue< $100K (42%)Email20%Phone55%Website36%

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A live view of all 4,528 biotech firms, sorted by revenue. Narrow it by region, city, employee size, revenue, legal form or founding year, or search a firm by name.

Amgen INC.Amgen INC.

	Company Name	Country	City	Address 1	State/Province	Postal Code	Website	Founding Year	Yearly Revenue in U.S. Dollars	Employees Total	Business Legal Type - Description	Number of Companies in Group	Company Registration Number
1	Amgen INC.	USA	Thousand Oaks	1 Amgen Center Dr	Santa Clara	91320-1799	*****.com	1980	$36,751,000,000	31,500	Corporation	184	2106150
2	Biogen INC.	USA	Cambridge	225 Binney St	Worcester	02142-1031	*****.com	1978	$9,890,600,000	7,500	Corporation	125	2726078
3	Neurocrine Biosciences, INC.	USA	San Diego	6027 Edgewood Bend Ct	San Diego	92130-8235	*****.com	1992	$2,860,500,000	2,000	Corporation	12	2604831
4	Exelixis, INC.	USA	Alameda	1851 Harbor Bay Pkwy	Alameda	94502	*****.com	1994	$2,320,126,000	1,077	Corporation	8	2452819
5	Seagen INC.	USA	Bothell	21823 30th Dr Se	King	98021-3907	*****.com	2023	$1,962,412,000	3,256	Corporation	702	F1862566
6	Moderna, INC.	USA	Cambridge	325 Binney St	Worcester	02142-1038	*****.com	2009	$1,944,000,000	4,700	Corporation	48	6104873
7	Csl Behring L.L.C.	USA	King of Prussia	1020 1st Ave	Montgomery	19406-1310	*****.com	1996	$1,759,357,880	5,800	Corporation	499	2506486
8	Emd Holding CORP.	USA	Boston	200 Pier 4 Blvd Ste 300	Suffolk	02210-2494	N/A	2010	$1,583,416,042	9,800	Corporation	728	001022746
9	Halozyme Therapeutics, INC.	USA	San Diego	12390 el Camino Real	San Diego	92130-3162	*****.com	1998	$1,396,611,000	425	Corporation	11	4406566
10	Repligen CORPORATION	USA	Waltham	41 Seyon St Ste 100	Middlesex	02453-8358	*****.com	1981	$738,256,000	2,000	Corporation	46	915374
11	Promega CORPORATION	USA	Madison	2800 Woods Hollow Rd	Dane	53711-5399	*****.com	1980	$690,571,000	2,092	Corporation	28	1 B16353
12	Kedrion Biopharma INC.	USA	Fort Lee	400 Kelby St Ste 11	Bergen	07024-2938	*****.com	2011	$629,807,595	850	Corporation	544	4958881
13	Dsm Nutritional Products, LLC	USA	Plainsboro	250 Plainsboro Rd	Middlesex	08536-1908	*****.com	1997	$523,764,583	1,265	Corporation	440	4904761
14	Adma Biologics, INC.	USA	Ramsey	465 State Rt 17	Bergen	07446	*****.com	2006	$510,173,000	647	Corporation	4	4168997
15	Tarsus Pharmaceuticals, INC.	USA	Irvine	15440 Laguna Canyon Rd Ste 160	Orange	92618-2143	*****.com	2016	$451,360,000	370	Corporation	2	6134500
16	Boehringer Ingelheim Animal Health USA INC.	USA	Johns Creek	4000 Medley Blvd Ste 300	Fulton	30097	*****.com	1917	$441,492,424	2,836	Corporation	370	921279
17	Integrated Dna Technologies, INC.	USA	Coralville	1710 Commercial Park	Johnson	52241-2760	*****.com	2018	$419,639,643	725	Corporation	756	117329
18	Krystal Biotech, INC.	USA	Pittsburgh	2100 Wharton St Ste 701	Allegheny	15203-1973	*****.com	2016	$389,130,000	295	Corporation	9	6365953
19	Twist Bioscience CORPORATION	USA	South San Francisco	681 Gateway Blvd	San Mateo	94080-7015	*****.com	2013	$376,572,000	979	Corporation	16	5283571
20	Biogen Ma INC.	USA	Cambridge	225 Binney St	Worcester	02142-1031	*****.com	2003	$370,960,917	500	Corporation	125	043002117
21	Denali Therapeutics INC.	USA	South San Francisco	161 Oyster Point Blvd	San Mateo	94080-2042	*****.com	2015	$330,531,000	503	Corporation	5	5414857
22	Dynavax Technologies CORPORATION	USA	Emeryville	2100 Powell St 7th Fl	Alameda	94608-1873	*****.com	2026	$277,246,000	405	Corporation	539	3302804
23	Vericel CORPORATION	USA	Burlington	25 Blue Sky Dr	Middlesex	01803	*****.com	1989	$276,259,000	398	Corporation	9	800549034
24	Iovance Biotherapeutics, INC.	USA	San Carlos	825 Industrial Rd Ste 100	San Mateo	94070-3303	*****.com	2011	$263,502,000	975	Corporation	16	6431490
25	Cerus CORPORATION	USA	Concord	1220 Concord Ave Ste 600	Orange	94520-4906	*****.com	1991	$233,798,000	345	Corporation	8	2648991

Showing 25 of 4,528 companies

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Where in the USA?

New York has the most biotech companies in the USA (78), ahead of San Diego (70), Cambridge (62), Phoenix (49) and Denver (39). Together the five hold one in fifteen of them.

Cities by number of firms

1,762 US cities have at least one biotech firm; 77 have ten or more; 1,106 have exactly one. Click a city to set the lens.

Biotech firms in New York

New York has 78 biotech companies and biotech firms, <0.1% of all 732,093 New York companies and 50% above the national share. Four in five New York firms have fewer than five people; 4 have 50 or more. 2 new firms were entered in 2026, 1 dates from before 1990.

Size

1-4 staff: 61 · 78%
5-9: 7 · 9%
10-19: 3 · 4%
20-49: 3 · 4%
50+: 4 · 5%

Legal form

Sole traders: 0 · 0%
Partnerships: 3 · 4%
Corporations and LLCs: 61 · 78%
Other or none: 14 · 18%

Of the US total: 1.7%
Of all New York companies: <0.1%
Against the national share: 1.5×

New

Entered 2026 so far: 2
Entered 2025: 3
Of USA's 2026 entries: 1.3%

Old

Before 1990: 1 · 1%
1990 or later: 77 · 99%
Of USA's pre-1990 firms: 0.9%

Reachable

Email: 18 · 23%
Phone: 47 · 60%
Website: 35 · 45%

Revenue (USD)

Under $100K: 19 · 25%
$100K-$500K: 41 · 53%
$500K-$1M: 1 · 1%
$1M and more: 16 · 21%

Largest

1403
2190
3127
492
551

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How many biotech companies are there in the USA?

Biotech companies and biotech firms in the USA

4,528

21 October 2026

There are 4,528 biotech companies and biotech firms in the USA in our data (21 October 2026). That is one in every 14,106 US companies. About 4 new firms are entered in the register every week this year (154 so far in 2026).

Structure

Single-site firms: 3,799 84%
Head offices: 304
Branch offices: 425

Classification

Our platform filter is SIC 2836.

3,211 of the 4,528 are corporations and LLCs (71%); 113 are sole traders. They come from the state business registers and our US register data, through the Company Data API.

Largest biotech firms in the USA

The biggest firms by staff and by revenue, the largest in New York. Click a name for the record.

Amgen is the largest biotech firm in the USA by headcount. 212 firms employ 50 people or more; 109 employ 100 or more.

1Thousand Oaks31,500 staff
2Lansdale8,207 staff
3Cambridge7,500 staff
4King of Prussia5,800 staff
5Cambridge4,700 staff
6Raleigh4,199 staff
7Bothell3,256 staff
8Johns Creek2,836 staff
9Madison2,092 staff
10San Diego2,000 staff

By employee size · 4,513 firms with a known headcount

Employees	Firms	%
1-4	3,454	77%
5-9	451	10%
10-19	191	4%
20-49	205	5%
50-99	103	2%
100-199	58	1%
200-499	38	0.8%
500-999	10	0.2%
1,000+	3	<0.1%

77% have 1 to 4 people; 205 have 20 to 49; 212 have 50 or more.

By yearly revenue (USD)

Revenue	Firms	%
< $100K	1,709	42%
$100K-$500K	1,692	41%
$500K-$1M	184	4%
$1M-$5M	238	6%
$5M-$10M	90	2%
$10M-$50M	106	3%
$50M-$100M	27	0.7%
$100M-$500M	29	0.7%
$500M+	14	0.3%

42% under $100,000; 238 between $1M and $5M; 266 above $5M.

Firm sizes in the USA

Of the 4,513 US biotech firms with a known headcount, 3,454 (77%) have one to four people, 451 have five to nine, 396 have ten to 49 and 212 have 50 or more. Most firms turn over under $100,000 a year (1,709, 42%).

EU size bands · the grey line shows all US companies

Micro under 103,905 87%
Small 10 to 49396 9%
Medium 50 to 249199 4%
Large 250+13 0.3%

Grey line: the share among all US companies (96% have under ten staff).

266

firms turn over more than $5 million a year; 176 more than $10 million.

154

firms were entered in 2026.

The oldest firms in the USA

Our data holds 1 US biotech firms from before 1900, 8 from before 1950 and 115 from before 1990.

1888
1. Irvine
1917
1. Johns Creek
1923
1. Denver
1934
1. Topeka
1941
1. Bellwood
1946
1. Lenoir

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1990

115

US biotech firms date from before 1990

were entered in 1990

Sole traders or corporations: how they are organised

One in forty US biotech firms work as sole traders, against 5% of all US companies. Seven in ten are corporations and LLCs.

Sole traders1132%
Partnerships742%
Corporations and LLCs3,21171%
No form on record or other1,13025%

Single-site: 84%
Head offices: 304
Branches: 425

All US companies: 5% sole traders, 1% partnerships, 68% corporations and LLCs.

Newcomers in the USA in 2026

154 biotech firms were entered in the US register so far in 2026, about 4 a week, after 227 in 2025. The USA as a whole saw 2,970,531 new companies in 2026, so this industry takes <0.1% of the inflow.

2492022
2432023
2852024
2272025
1542026 so far

152 of this year's 154 are corporations and LLCs.

The biggest newcomers of 2026

The year is the register entry; an established firm that changes legal form appears as new.

1Redwood Shores209 staff
2Waterville112 staff
3Troutdale94 staff
4Piscataway58 staff
5San Diego38 staff

How reachable are they?

Biotech firms are easier to reach than the average US company: 55% list a phone number and 36% a website.

Email925 20%
Phone2,500 55%
Website1,616 36%

Grey line: all US companies (email 15%, phone 42%, website 24%).

The full list with these fields is in our US company database.

How they compare

Next to related industries

There are 397 healthcare companies for every biotech firm in the USA.

Industry	Firms	Website	1-4 staff
Healthcare Companies	1,795,850	32%	82%
Laboratories	125,256	28%	85%
Chemical Companies	103,379	40%	70%
Pharmaceutical Companies	57,731	38%	73%
Medical Device Companies	10,237	55%	54%
Biotech Companies	4,528	36%	76%

In other countries

The USA has more biotech firms than India or New Zealand.

Country	Firms	Per 1,000 cos.
The USA	4,528	0.1
India	812	0.0
New Zealand	178	0.2
Singapore	84	0.1
Vietnam	28	0.0

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Free sample: biotech firms in North America

Frequently asked questions

How many biotech companies are there in the USA?

There are 4,528 biotech companies and biotech firms in the USA in our data, counted on 21 October 2026. That is one in every 14,106 US companies.

Which is the largest biotech firm in the USA?

Amgen in Thousand Oaks, with 31,500 staff.

Which US city has the most biotech companies?

New York, with 78, ahead of San Diego (70), Cambridge (62), Phoenix (49) and Denver (39).

How many biotech firms are there in New York?

78, which is <0.1% of all 732,093 New York companies and 50% above the national share.

How big is a typical biotech firm?

Small. 77% of the 4,513 firms with a known headcount have one to four people; 212 have 50 or more. Most turn over under $100,000 a year.

Are US biotech companies sole traders or companies?

One in forty (113) are sole traders, 2% are partnerships and 71% (3,211) are corporations and LLCs.

How many biotech firms started in 2026?

154 were entered in the US register so far in 2026, after 227 in 2025. 152 of them are corporations and LLCs.

What is the oldest biotech firm in the USA?

Biomems in Irvine, 1888, followed by Boehringer Ingelheim Animal Health USA in Johns Creek (1917) and Colorado Serum in Denver (1923). 1 firm dates from before 1900.

Which industry code covers biotech companies?

Our platform filters them on SIC 2836 (biological products, except diagnostic substances).

Can I download the full list?

Yes. All 4,528 firms with address, phone, email, legal form, employees, revenue and founding year, as Excel, CSV or through the API.

Discover more: related industries, by city, in other countries

The lists closest to this one. Every industry and city in the USA is on the USA page.

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